产品详情
简单介绍：
Anti-ARHU/WRCH1 antibody (N-Term) (STJ70145)
详情介绍：
| Host: | Goat |
| Applications: | Pep-ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Goat polyclonal antibody anti-ARHU/WRCH1 (N-Term) is suitable for use in ELISA research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | ELISA-antibody detection limit dilution 1:16000. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | RHOU |
| Gene ID: | 58480 |
| Uniprot ID: | RHOU_HUMAN |
| Immunogen Region: | N-Term |
| Accession Number: | NP_067028.1 |
| Immunogen Sequence: | PPQQGDPAFPDRCEA |
| Post Translational Modifications | Tyrosine phosphorylated by SRC in response to PTK2B/PYK2 activation. |
| Function | Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. |
| Protein Name | Rho-Related Gtp-Binding Protein Rhou Cdc42-Like Gtpase 1 Gtp-Binding Protein-Like 1 Rho Gtpase-Like Protein Arhu Ryu Gtpase Wnt-1 Responsive Cdc42 Homolog 1 Wrch-1 |
| Database Links | Reactome: R-HSA-6785807 Reactome: R-HSA-9013420 |
| Cellular Localisation | Cell Membrane Lipid-Anchor Cytoplasmic Side Golgi Apparatus Membrane Cell Junction Focal Adhesion Cell Projection Podosome Localizes To Podosomes In Src-Transformed Cells |
| Alternative Antibody Names | Anti-Rho-Related Gtp-Binding Protein Rhou antibody Anti-Cdc42-Like Gtpase 1 antibody Anti-Gtp-Binding Protein-Like 1 antibody Anti-Rho Gtpase-Like Protein Arhu antibody Anti-Ryu Gtpase antibody Anti-Wnt-1 Responsive Cdc42 Homolog 1 antibody Anti-Wrch-1 antibody Anti-RHOU antibody Anti-ARHU antibody Anti-CDC42L1 antibody Anti-G28K antibody Anti-WRCH1 antibody Anti-SB128 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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