产品详情
  • 产品名称:Anti-ARX antibody (Internal) (STJ73488)

  • 产品型号:STJ73488-100
  • 产品厂商:ST john's laboratory
  • 产品文档:
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简单介绍:
Anti-ARX antibody (Internal) (STJ73488)
详情介绍:
Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat/Dog
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-ARX (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.5-1µg/ml
ELISA-antibody detection limit dilution 1:1000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: ARX
Gene ID: 170302
Uniprot ID: ARX_HUMAN
Immunogen Region: Internal
Accession Number: NP_620689.1
Immunogen Sequence: QVSISRSKSYREN
Function Transcription factor. Binds to specific sequence motif 5'-TAATTA-3' in regulatory elements of target genes, such as histone demethylase KDM5C. Positively modulates transcription of KDM5C. Activates expression of KDM5C synergistically with histone lysine demethylase PHF8 and perhaps in competition with transcription regulator ZNF711.synergy may be related to enrichment of histone H3K4me3 in regulatory elements. Required for normal brain development. Plays a role in neuronal proliferation, interneuronal migration and differentiation in the embryonic forebrain. May also be involved in axonal guidance in the floor plate.
Protein Name Homeobox Protein Arx
Aristaless-Related Homeobox
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Homeobox Protein Arx antibody
Anti-Aristaless-Related Homeobox antibody
Anti-ARX antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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