产品详情
简单介绍:
Anti-Butyrylcholinesterase antibody (500-602) [S6MR] (STJ11103636)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit monoclonal antibody anti-Butyrylcholinesterase (500-602) is suitable for use in Western Blot research applications. |
Clonality: | Monoclonal |
Clone ID: | S6MR |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:1000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | BCHE |
Gene ID: | 590 |
Uniprot ID: | CHLE_HUMAN |
Immunogen Region: | 500-602 |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-602 of human Butyrylcholinesterase (P06276). |
Immunogen Sequence: | ANFAKYGNPNETQNNSTSWP VFKSTEQKYLTLNTESTRIM TKLRAQQCRFWTSFFPKVLE MTGNIDEAEWEWKAGFHRWN NYMMDWKNQFNDYTSKKESC VGL |
Tissue Specificity | Detected in blood plasma (at protein level). Present in most cells except erythrocytes. |
Post Translational Modifications | N-glycosylated. No other PTM detected. The major N-glycan structures are of the complex diantennary type with 1 and 2 N-acetylneuraminic acid molecules (Neu5Ac) making up approximately 33% and 47% of the total N-glycans, respectively. Only low amounts of fucosylated diantennary N-glycans are detected (approximately 2%). Triantennary N-glycans with or without fucose amount to approximately 13%, whereas 5% of the total N-glycans are of the oligomannosidic or hybrid type. |
Function | Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters. |
Protein Name | Cholinesterase Acylcholine Acylhydrolase Butyrylcholine Esterase Choline Esterase Ii Pseudocholinesterase |
Database Links | Reactome: R-HSA-112311 Reactome: R-HSA-1483191 Reactome: R-HSA-422085 Reactome: R-HSA-9749641 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Cholinesterase antibody Anti-Acylcholine Acylhydrolase antibody Anti-Butyrylcholine Esterase antibody Anti-Choline Esterase Ii antibody Anti-Pseudocholinesterase antibody Anti-BCHE antibody Anti-CHE1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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