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  • 产品名称：Anti-C4BPB antibody (17-251) (STJ28445)

  • 产品型号：STJ28445
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-C4BPB antibody (17-251) (STJ28445)
详情介绍：
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-C4BPB (17-251) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: C4BPB
Gene ID: 725
Uniprot ID: C4BPB_HUMAN
Immunogen Region: 17-251
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-251 of human C4BPB (NP_001017364.1).
Immunogen Sequence: ASDEHCPELPPVDNSIFVAK EVEGQILGTYVCIKGYHLVG KKTLFCNASKEWDNTTTECR LGHCPDPVLVNGEFSSSGPV NVSDKITFMCNDHYILKGSN RSQCLEDHTWAPPFPICKSR DCDPPGNPVHGYFEGNNFTL GSTISYYCEDRYYLVGVQEQ QCVDGEWSSALPVCKLIQEA PKPECEKALLAFQESKNLCE AMENFMQQLKESGMTMEELK YSLELKKAELKAKLL
Function Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S.
Protein Name C4b-Binding Protein Beta Chain
Database Links Reactome: R-HSA-977606
Cellular Localisation Secreted
Alternative Antibody Names Anti-C4b-Binding Protein Beta Chain antibody
Anti-C4BPB antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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