产品详情
简单介绍：
Anti-ASIC2 antibody (470-503) (STJ13100481)
详情介绍：
| Host: | NZ White Rabbit |
| Applications: | IHC/WB |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Nz White Rabbit polyclonal antibody anti-ASIC2 (470-503) is suitable for use in Immunohistochemistry and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Shipped as lyophilised. Reconstitute in 500 µl of sterile water. Centrifuge to remove any insoluble material. |
| Purification: | Ammonium sulphate precipitation |
| Dilution Range: | A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications. |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | Asic2 |
| Gene ID: | 25364 |
| Uniprot ID: | ASIC2_RAT |
| Immunogen Region: | 470-503 |
| Specificity: | Specific for ASIC2. |
| Immunogen: | A synthetic peptide from aa region 470-503 of human ASIC2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse. |
| Function | Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Activation by an extracellular pH drop is followed by a rapid pH-independent inactivation. Heteromeric channel assembly seems to modulate channel properties. |
| Protein Name | Acid-Sensing Ion Channel 2 Asic2 Amiloride-Sensitive Brain Sodium Channel Amiloride-Sensitive Brain Sodium Channel 2 Amiloride-Sensitive Cation Channel 1 - Neuronal Amiloride-Sensitive Cation Channel Neuronal 1 Brain Sodium Channel 1 Bnc1 Bnac1 Mammalian Degenerin Homolog Mdeg |
| Database Links | Reactome: R-RNO-2672351 |
| Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein Localized At The Plasma Membrane Of Neurons In The Soma And Punctated Peripheral Processes |
| Alternative Antibody Names | Anti-Acid-Sensing Ion Channel 2 antibody Anti-Asic2 antibody Anti-Amiloride-Sensitive Brain Sodium Channel antibody Anti-Amiloride-Sensitive Brain Sodium Channel 2 antibody Anti-Amiloride-Sensitive Cation Channel 1 - Neuronal antibody Anti-Amiloride-Sensitive Cation Channel Neuronal 1 antibody Anti-Brain Sodium Channel 1 antibody Anti-Bnc1 antibody Anti-Bnac1 antibody Anti-Mammalian Degenerin Homolog antibody Anti-Mdeg antibody Anti-Asic2 antibody Anti-Accn1 antibody Anti-Bnac1 antibody Anti-Mdeg antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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