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  • 产品名称：Human HEXb (Hexosaminidase B Beta) Sandwich ELISA Kit (STJE0009439)

  • 产品型号：STJE0009439
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human HEXb (Hexosaminidase B Beta) Sandwich ELISA Kit (STJE0009439)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.058ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This HEXb Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: HEXB
Gene ID: 3074
Uniprot ID: HEXB_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications N-linked glycans at Asn-142 and Asn-190 consist of Man(3)-GlcNAc(2) and Man(5 to 7)-GlcNAc(2), respectively. The beta-A and beta-B chains are produced by proteolytic processing of the precursor beta chain.
Function Hydrolyzes the non-reducing end N-acetyl-D-hexosamine and/or sulfated N-acetyl-D-hexosamine of glycoconjugates, such as the oligosaccharide moieties from proteins and neutral glycolipids, or from certain mucopolysaccharides. The isozyme B does not hydrolyze each of these substrates, however hydrolyzes efficiently neutral oligosaccharide. Only the isozyme A is responsible for the degradation of GM2 gangliosides in the presence of GM2A. During fertilization is responsible, at least in part, for the zona block to polyspermy. Present in the cortical granules of non-activated oocytes, is exocytosed during the cortical reaction in response to oocyte activation and inactivates the sperm galactosyltransferase-binding site, accounting for the block in sperm binding to the zona pellucida.
Protein Name Beta-Hexosaminidase Subunit Beta
Beta-N-Acetylhexosaminidase Subunit Beta
Hexosaminidase Subunit B
Cervical Cancer Proto-Oncogene 7 Protein
Hcc-7
N-Acetyl-Beta-Glucosaminidase Subunit Beta Cleaved Into - Beta-Hexosaminidase Subunit Beta Chain B - Beta-Hexosaminidase Subunit Beta Chain A
Database Links Reactome: R-HSA-1660662
Reactome: R-HSA-2022857
Reactome: R-HSA-2024101
Reactome: R-HSA-2160916
Reactome: R-HSA-3656248
Reactome: R-HSA-6798695
Cellular Localisation Lysosome
Cytoplasmic Vesicle
Secretory Vesicle
Cortical Granule
Alternative ELISA Names Beta-Hexosaminidase Subunit Beta ELISA kit
Beta-N-Acetylhexosaminidase Subunit Beta ELISA kit
Hexosaminidase Subunit B ELISA kit
Cervical Cancer Proto-Oncogene 7 Protein ELISA kit
Hcc-7 ELISA kit
N-Acetyl-Beta-Glucosaminidase Subunit Beta Cleaved Into - Beta-Hexosaminidase Subunit Beta Chain B - Beta-Hexosaminidase Subunit Beta Chain A ELISA kit
HEXB ELISA kit
HCC7 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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