产品详情
简单介绍:
Anti-CACNA1D antibody (1060-1140 aa) (STJ197416)
详情介绍:
Host: | Rabbit |
Applications: | IHC/IF |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Voltage-dependent L-type calcium channel subunit alpha-1D (1060-1140 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | IHC 1:100-200 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CACNA1D |
Gene ID: | 776 |
Uniprot ID: | CAC1D_HUMAN |
Immunogen Region: | 1060-1140 aa |
Specificity: | Cav1.3 protein (A202) detects endogenous levels of Cav1.3 |
Immunogen: | Synthetic peptide derived from Cav1.3 at the amino acid range 1060-1140 |
Function | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines. |
Protein Name | Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1d Calcium Channel - L Type - Alpha-1 Polypeptide - Isoform 2 Voltage-Gated Calcium Channel Subunit Alpha Cav1.3 |
Database Links | Reactome: R-HSA-400042 Reactome: R-HSA-419037 Reactome: R-HSA-422356 Reactome: R-HSA-9662360 |
Cellular Localisation | Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1d antibody Anti-Calcium Channel - L Type - Alpha-1 Polypeptide - Isoform 2 antibody Anti-Voltage-Gated Calcium Channel Subunit Alpha Cav1.3 antibody Anti-CACNA1D antibody Anti-CACH3 antibody Anti-CACN4 antibody Anti-CACNL1A2 antibody Anti-CCHL1A2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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