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  • 产品名称：Anti-CALCR antibody (25-148) (STJ11103819)

  • 产品型号：STJ11103819
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CALCR antibody (25-148) (STJ11103819)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Calcitonin Receptor (25-148) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CALCR
Gene ID: 799
Uniprot ID: CALCR_HUMAN
Immunogen Region: 25-148
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-148 of human CALCR (NP_001733.1).
Immunogen Sequence: AFSNQTYPTIEPKPFLYVVG RKKMMDAQYKCYDRMQQLPA YQGEGPYCNRTWDGWLCWDD TPAGVLSYQFCPDYFPDFDP SEKVTKYCDEKGVWFKHPEN NRTWSNYTMCNAFTPEKLKN AYVL
Function This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. Isoform 2: Receptor for calcitonin but is unable to couple to G proteins and activate adenylyl cyclase. Does not undergo receptor internalization following ligand binding.
Protein Name Calcitonin Receptor
Ct-R
Database Links Reactome: R-HSA-418555
Reactome: R-HSA-419812
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Calcitonin Receptor antibody
Anti-Ct-R antibody
Anti-CALCR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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