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  • 产品名称：Anti-CAMKK1 antibody (STJA0010268)

  • 产品型号：STJA0010268
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CAMKK1 antibody (STJA0010268)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Calcium/calmodulin-dependent protein kinase kinase 1 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAMKK1
Gene ID: 84254
Uniprot ID: KKCC1_HUMAN
Specificity: This antibody detects endogenous levels of CAMKK1/2 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human CAMKK1/2
Post Translational Modifications Appears to be autophosphorylated in a Ca(2+)/calmodulin-dependent manner. Phosphorylated at multiple sites by PRCAKA/PKA. Phosphorylation of Ser-458 is blocked upon binding to Ca(2+)/calmodulin. In vitro, phosphorylated by CAMK1 and CAMK4.
Function Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2-antagonist of cell death.
Protein Name Calcium/Calmodulin-Dependent Protein Kinase Kinase 1
Cam-Kk 1
Cam-Kinase Kinase 1
Camkk 1
Cam-Kinase Iv Kinase
Calcium/Calmodulin-Dependent Protein Kinase Kinase Alpha
Cam-Kk Alpha
Cam-Kinase Kinase Alpha
Camkk Alpha
Database Links Reactome: R-HSA-111932
Reactome: R-HSA-442729
Reactome: R-HSA-9619229
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Calcium/Calmodulin-Dependent Protein Kinase Kinase 1 antibody
Anti-Cam-Kk 1 antibody
Anti-Cam-Kinase Kinase 1 antibody
Anti-Camkk 1 antibody
Anti-Cam-Kinase Iv Kinase antibody
Anti-Calcium/Calmodulin-Dependent Protein Kinase Kinase Alpha antibody
Anti-Cam-Kk Alpha antibody
Anti-Cam-Kinase Kinase Alpha antibody
Anti-Camkk Alpha antibody
Anti-CAMKK1 antibody
Anti-CAMKKA antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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