产品详情
查看大图

  • 产品名称：Anti-CAMKK2 antibody (381-430 aa) (STJ91989)

  • 产品型号：STJ91989
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Anti-CAMKK2 antibody (381-430 aa) (STJ91989)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Calcium/calmodulin-dependent protein kinase kinase 2 (381-430 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAMKK2
Gene ID: 10645
Uniprot ID: KKCC2_HUMAN
Immunogen Region: 381-430 aa
Specificity: CaMKII Beta Polyclonal Antibody detects endogenous levels of CaMKII Beta protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CAMKK2 at the amino acid range 381-430
Post Translational Modifications Autophosphorylated and phosphorylated by PKA. Each isoform may show a different pattern of phosphorylation.
Function Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals. Seems to be involved in hippocampal activation of CREB1. May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
Protein Name Calcium/Calmodulin-Dependent Protein Kinase Kinase 2
Cam-Kk 2
Cam-Kinase Kinase 2
Camkk 2
Calcium/Calmodulin-Dependent Protein Kinase Kinase Beta
Cam-Kk Beta
Cam-Kinase Kinase Beta
Camkk Beta
Database Links Reactome: R-HSA-111932
Reactome: R-HSA-442729
Reactome: R-HSA-9619229
Reactome: R-HSA-9619483
Cellular Localisation Nucleus
Cytoplasm
Cell Projection
Neuron Projection
Predominantly Nuclear In Unstimulated Cells
Relocalizes Into Cytoplasm And Neurites After Forskolin Induction
Alternative Antibody Names Anti-Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 antibody
Anti-Cam-Kk 2 antibody
Anti-Cam-Kinase Kinase 2 antibody
Anti-Camkk 2 antibody
Anti-Calcium/Calmodulin-Dependent Protein Kinase Kinase Beta antibody
Anti-Cam-Kk Beta antibody
Anti-Cam-Kinase Kinase Beta antibody
Anti-Camkk Beta antibody
Anti-CAMKK2 antibody
Anti-CAMKKB antibody
Anti-KIAA0787 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号