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  • 产品名称：Human HSPA1L (Heat Shock 70kDa Protein 1 Like Protein) Sandwich ELISA Kit Ready-To-Use (STJE0015945)

  • 产品型号：STJE0015945
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human HSPA1L (Heat Shock 70kDa Protein 1 Like Protein) Sandwich ELISA Kit Ready-To-Use (STJE0015945)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.063ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This HSPA1L Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: HSPA1L
Gene ID: 3305
Uniprot ID: HS71L_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Expressed in spermatids.
Post Translational Modifications
Function Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins. However, upon hydrolysis of the ATP to ADP, it undergoes a conformational change that increases its affinity for substrate proteins. It goes through repeated cycles of ATP hydrolysis and nucleotide exchange, which permits cycles of substrate binding and release. Positive regulator of PRKN translocation to damaged mitochondria.
Protein Name Heat Shock 70 Kda Protein 1-Like
Heat Shock 70 Kda Protein 1l
Heat Shock 70 Kda Protein 1-Hom
Hsp70-Hom
Database Links Reactome: R-HSA-3371453
Reactome: R-HSA-3371497
Reactome: R-HSA-3371568
Reactome: R-HSA-3371571
Cellular Localisation
Alternative ELISA Names Heat Shock 70 Kda Protein 1-Like ELISA kit
Heat Shock 70 Kda Protein 1l ELISA kit
Heat Shock 70 Kda Protein 1-Hom ELISA kit
Hsp70-Hom ELISA kit
HSPA1L ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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