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  • 产品名称：Anti-CANX antibody (550 aa C-Term) {DyLight®550} (STJ140257)

  • 产品型号：STJ140257
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CANX antibody (550 aa C-Term) {DyLight®550} (STJ140257)
详情介绍：
Host: Goat
Applications: WB/IHC-F/IF
Reactivity: Human/Rat/Mouse/Canine/Monkey
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-CANX (550 aa C-Term) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: DyLight®550
Isotype: IgG
Formulation: PBS, 20% Glycerol, 0.05% ProClin® and 0.05% Sodium Azide.
Purification: Epitope affinity purified
Concentration: 2 mg/ml
Dilution Range: WB 1:500-1:5000
IHC-F 1:50-1:500
IF 1:200-1:1000
Storage Instruction: For continuous use, store at 2-8 C for one-two days. For extended storage, store in-20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
Gene Symbol: CANX
Gene ID: 821
Uniprot ID: CALX_HUMAN
Immunogen Region: 550 aa C-Term
Specificity: Detects a band of 90 kDa by Western blot whole cell lysates.
Immunogen: Purified recombinant peptide within residues 550 aa to the C-terminus of human CANX produced in E. coli.
Function Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.
Protein Name Calnexin
Ip90
Major Histocompatibility Complex Class I Antigen-Binding Protein P88
P90
Database Links Reactome: R-HSA-168316
Reactome: R-HSA-2132295
Reactome: R-HSA-8984722
Reactome: R-HSA-901042
Reactome: R-HSA-9020956
Reactome: R-HSA-9683686
Reactome: R-HSA-9694548
Reactome: R-HSA-983170
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type I Membrane Protein
Endoplasmic Reticulum
Melanosome
Identified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv
The Palmitoylated Form Preferentially Localizes To The Perinuclear Rough Er
Alternative Antibody Names Anti-Calnexin antibody
Anti-Ip90 antibody
Anti-Major Histocompatibility Complex Class I Antigen-Binding Protein P88 antibody
Anti-P90 antibody
Anti-CANX antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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