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  • 产品名称：Anti-CAPN2 antibody (600-700) [S9MR] (STJ11101989)

  • 产品型号：STJ11101989
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CAPN2 antibody (600-700) [S9MR] (STJ11101989)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit monoclonal antibody anti-Calpain 2 (600-700) is suitable for use in Western Blot research applications.
Clonality: Monoclonal
Clone ID: S9MR
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAPN2
Gene ID: 824
Uniprot ID: CAN2_HUMAN
Immunogen Region: 600-700
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 600-700 of human Calpain 2 (P17655).
Immunogen Sequence: LWTKIQKYQKIYREIDVDRS GTMNSYEMRKALEEAGFKMP CQLHQVIVARFADDQLIIDF DNFVRCLVRLETLFKIFKQL DPENTGTIELDLISWLCFSV L
Tissue Specificity Ubiquitous.
Function Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs.
Protein Name Calpain-2 Catalytic Subunit
Calcium-Activated Neutral Proteinase 2
Canp 2
Calpain M-Type
Calpain Large Polypeptide L2
Calpain-2 Large Subunit
Millimolar-Calpain
M-Calpain
Database Links Reactome: R-HSA-1474228
Reactome: R-HSA-8862803
Cellular Localisation Cytoplasm
Cell Membrane
Translocates To The Plasma Membrane Upon Ca(2+) Binding
Alternative Antibody Names Anti-Calpain-2 Catalytic Subunit antibody
Anti-Calcium-Activated Neutral Proteinase 2 antibody
Anti-Canp 2 antibody
Anti-Calpain M-Type antibody
Anti-Calpain Large Polypeptide L2 antibody
Anti-Calpain-2 Large Subunit antibody
Anti-Millimolar-Calpain antibody
Anti-M-Calpain antibody
Anti-CAPN2 antibody
Anti-CANPL2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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