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  • 产品名称：Anti-ATOH7 antibody (47-152) (STJ29412)

  • 产品型号：STJ29412
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-ATOH7 antibody (47-152) (STJ29412)
详情介绍：
Host: Rabbit
Applications: WB/IF
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-ATOH7 (47-152) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:100
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ATOH7
Gene ID: 220202
Uniprot ID: ATOH7_HUMAN
Immunogen Region: 47-152
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 47-152 of human ATOH7 (NP_660161.1).
Immunogen Sequence: ARERRRMQGLNTAFDRLRRV VPQWGQDKKLSKYETLQMAL SYIMALTRILAEAERFGSER DWVGLHCEHFGRDHYLPFPG AKLPGESELYSQRLFGFQPE PFQMAT
Function Transcription factor that binds to DNA at the consensus sequence 5'-CAGGCTG-3'. Dimerization with TCF3 isoform E47 may be required in certain situations. Binds to gene promoters and enhancer elements, and thereby regulates a transcriptional program of retinal ganglion cell (RGC) determinant genes. Although the exact mechanism is not certain, retinal transcription regulation by ATOH7 has a role in RGC determination and survival, photoreceptor population development, targeting of RGC axons to the optic nerve and development of the retino-hypothalamic tract. Binds to its own promoter and enhancer sequences, suggesting autoregulation of ATOH7 transcription. Required for retinal circadian rhythm photoentrainment. Plays a role in brainstem auditory signaling and binaural processing.
Protein Name Transcription Factor Atoh7
Atonal Bhlh Transcription Factor 7
Class A Basic Helix-Loop-Helix Protein 13
Bhlha13
Protein Atonal Homolog 7
Cellular Localisation Nucleus
Perikaryon
Cell Projection
Axon
Alternative Antibody Names Anti-Transcription Factor Atoh7 antibody
Anti-Atonal Bhlh Transcription Factor 7 antibody
Anti-Class A Basic Helix-Loop-Helix Protein 13 antibody
Anti-Bhlha13 antibody
Anti-Protein Atonal Homolog 7 antibody
Anti-ATOH7 antibody
Anti-ATH5 antibody
Anti-BHLHA13 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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