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  • 产品名称：Human IL17C (Interleukin 17C) Sandwich ELISA Kit (STJE0009805)

  • 产品型号：STJE0009805
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human IL17C (Interleukin 17C) Sandwich ELISA Kit (STJE0009805)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 6.1pg/mL
Detection Limit: 15.6-1000pg/mL
Short Description: This IL17C Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: IL17C
Gene ID: 27189
Uniprot ID: IL17C_HUMAN
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and pro-inflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.
Protein Name Interleukin-17c
Il-17c
Cytokine Cx2
Database Links Reactome: R-HSA-448424
Cellular Localisation Secreted
Alternative ELISA Names Interleukin-17c ELISA kit
Il-17c ELISA kit
Cytokine Cx2 ELISA kit
IL17C ELISA kit
UNQ561 ELISA kit
PRO1122 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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