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  • 产品名称：Anti-CBR4 antibody (1-237) (STJ27063)

  • 产品型号：STJ27063
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CBR4 antibody (1-237) (STJ27063)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CBR4 (1-237) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CBR4
Gene ID: 84869
Uniprot ID: CBR4_HUMAN
Immunogen Region: 1-237
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-237 of human CBR4 (NP_116172.2).
Immunogen Sequence: MDKVCAVFGGSRGIGRAVAQ LMARKGYRLAVIARNLEGAK AAAGDLGGDHLAFSCDVAKE HDVQNTFEELEKHLGRVNFL VNAAGINRDGLLVRTKTEDM VSQLHTNLLGSMLTCKAAMR TMIQQQGGSIVNVGSIVGLK GNSGQSVYSASKGGLVGFSR ALAKEVARKKIRVNVVAPGF VHTDMTKDLKEEHLKKNIPL GRFGETIEVAHAVVFLLESP YITGHVLVVDGGLQLIL
Tissue Specificity Detected in liver and kidney (at protein level). Displays the highest expression in neuronal and muscle tissues.
Function Component of the heterotetramer complex KAR (3-ketoacyl-acyl carrier protein reductase or 3-ketoacyl-ACP reductase) that forms part of the mitochondrial fatty acid synthase (mtFAS). Beta-subunit of the KAR heterotetramer complex, responsible for the 3-ketoacyl-ACP reductase activity of the mtFAS, reduces 3-oxoacyl-ACP to (3R)-hydroxyacyl-ACP in a NADPH-dependent manner with no chain length preference, thereby participating in mitochondrial fatty acid biosynthesis. The homotetramer has NADPH-dependent quinone reductase activity (in vitro), hence could play a role in protection against cytotoxicity of exogenous quinones. As a heterotetramer, it can also reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones (in vitro).
Protein Name 3-Oxoacyl-Acyl-Carrier-Protein Reductase
3-Ketoacyl-Acyl-Carrier-Protein Reductase Beta Subunit
Kar Beta Subunit
Carbonyl Reductase Family Member 4
Cbr4
Quinone Reductase Cbr4
Short Chain Dehydrogenase/Reductase Family 45c Member 1
Database Links Reactome: R-HSA-75105
Cellular Localisation Mitochondrion Matrix
Alternative Antibody Names Anti-3-Oxoacyl-Acyl-Carrier-Protein Reductase antibody
Anti-3-Ketoacyl-Acyl-Carrier-Protein Reductase Beta Subunit antibody
Anti-Kar Beta Subunit antibody
Anti-Carbonyl Reductase Family Member 4 antibody
Anti-Cbr4 antibody
Anti-Quinone Reductase Cbr4 antibody
Anti-Short Chain Dehydrogenase/Reductase Family 45c Member 1 antibody
Anti-CBR4 antibody
Anti-SDR45C1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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