产品详情
简单介绍:
Human GPIHBP1 (Glycosylphosphatidylinositol Anchored High Density Lipoprotein Binding Protein 1) Sandwich ELISA Kit Ready-To-Use (STJE0015647)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.054ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This GPIHBP1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | GPIHBP1 |
Gene ID: | 338328 |
Uniprot ID: | HDBP1_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | Glycosylation of Asn-78 is critical for cell surface localization. Sulfation of a Tyr in the N-terminal acidic region increases the affinity for LPL. |
Function | Mediates the transport of lipoprotein lipase LPL from the basolateral to the apical surface of endothelial cells in capillaries. Anchors LPL on the surface of endothelial cells in the lumen of blood capillaries. Protects LPL against loss of activity, and against ANGPTL4-mediated unfolding. Thereby, plays an important role in lipolytic processing of chylomicrons by LPL, triglyceride metabolism and lipid homeostasis. Binds chylomicrons and phospholipid particles that contain APOA5. Binds high-density lipoprotein (HDL) and plays a role in the uptake of lipids from HDL. |
Protein Name | Glycosylphosphatidylinositol-Anchored High Density Lipoprotein-Binding Protein 1 Gpi-Hbp1 Gpi-Anchored Hdl-Binding Protein 1 High Density Lipoprotein-Binding Protein 1 |
Database Links | Reactome: R-HSA-163125 Reactome: R-HSA-8963889 Reactome: R-HSA-8963901 Reactome: R-HSA-975634 |
Cellular Localisation | Apical Cell Membrane Lipid-Anchor Gpi-Anchor Basolateral Cell Membrane Cell Membrane |
Alternative ELISA Names | Glycosylphosphatidylinositol-Anchored High Density Lipoprotein-Binding Protein 1 ELISA kit Gpi-Hbp1 ELISA kit Gpi-Anchored Hdl-Binding Protein 1 ELISA kit High Density Lipoprotein-Binding Protein 1 ELISA kit GPIHBP1 ELISA kit HBP1 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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