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  • 产品名称：Anti-CARMIL1 antibody (853-903 aa) (STJ195878)

  • 产品型号：STJ195878
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CARMIL1 antibody (853-903 aa) (STJ195878)
详情介绍：
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-F-actin-uncapping protein LRRC16A (853-903 aa) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CARMIL1
Gene ID: 55604
Uniprot ID: CARL1_HUMAN
Immunogen Region: 853-903 aa
Specificity: This antibody detects endogenous levels of LR16A at Human/Mouse
Immunogen: Synthesized peptide derived from the human LR16A at the amino acid range 853-903
Function Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments. Plays a role in lamellipodial protrusion formations and cell migration.
Protein Name F-Actin-Uncapping Protein Lrrc16a
Carmil Homolog
Capping Protein Regulator And Myosin 1 Linker Protein 1
Capping Protein - Arp2/3 And Myosin-I Linker Homolog 1
Capping Protein - Arp2/3 And Myosin-I Linker Protein 1
Leucine-Rich Repeat-Containing Protein 16a
Database Links Reactome: R-HSA-983231
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Membrane
Cell Projection
Lamellipodium
Found On Macropinosomes
Colocalized With Heterodimeric Capping Protein (Cp) And F-Actin In Lamellipodia But Not With F-Actin In Stress Fibers
Alternative Antibody Names Anti-F-Actin-Uncapping Protein Lrrc16a antibody
Anti-Carmil Homolog antibody
Anti-Capping Protein Regulator And Myosin 1 Linker Protein 1 antibody
Anti-Capping Protein - Arp2/3 And Myosin-I Linker Homolog 1 antibody
Anti-Capping Protein - Arp2/3 And Myosin-I Linker Protein 1 antibody
Anti-Leucine-Rich Repeat-Containing Protein 16a antibody
Anti-CARMIL1 antibody
Anti-CARMIL antibody
Anti-LRRC16 antibody
Anti-LRRC16A antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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