产品详情
查看大图

  • 产品名称：Anti-CASQ1 antibody (322-372 aa) (STJ194071)

  • 产品型号：STJ194071
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Anti-CASQ1 antibody (322-372 aa) (STJ194071)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Calsequestrin-1 (322-372 aa) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CASQ1
Gene ID: 844
Uniprot ID: CASQ1_HUMAN
Immunogen Region: 322-372 aa
Specificity: This antibody detects endogenous levels of CASQ1 at Human/Mouse/Rat
Immunogen: Synthesized peptide derived from the human CASQ1 at the amino acid range 322-372
Post Translational Modifications N-glycosylated.
Function Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits. Can bind around 80 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1.this plays an important role in triggering muscle contraction. Negatively regulates store-operated Ca(2+) entry (SOCE) activity.
Protein Name Calsequestrin-1
Calmitine
Calsequestrin - Skeletal Muscle Isoform
Database Links Reactome: R-HSA-2672351
Reactome: R-HSA-5578775
Cellular Localisation Endoplasmic Reticulum
Sarcoplasmic Reticulum
Sarcoplasmic Reticulum Lumen
Sarcoplasmic Reticulum Membrane
Peripheral Membrane Protein
Lumenal Side
Mitochondrion Matrix
This Isoform Of Calsequestrin Occurs In The Sarcoplasmic Reticulum's Terminal Cisternae Luminal Spaces Of Fast Skeletal Muscle Cells
Preferentially Forms Linear And Round Aggregates In The Endoplasmic Reticulum (Er) Of Resting Cells
In A Minority Of Cells
Homogeneously Detected In The Er Lumen
Colocalizes With Stim1 At Endoplasmic Reticulum In Response To A Depletion Of Intracellular Calcium
Alternative Antibody Names Anti-Calsequestrin-1 antibody
Anti-Calmitine antibody
Anti-Calsequestrin - Skeletal Muscle Isoform antibody
Anti-CASQ1 antibody
Anti-CASQ antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号