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  • 产品名称：Anti-CBLL1 antibody (STJA0007248)

  • 产品型号：STJA0007248
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CBLL1 antibody (STJA0007248)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-E3 ubiquitin-protein ligase Hakai is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CBLL1
Gene ID: 79872
Uniprot ID: HAKAI_HUMAN
Specificity: This antibody detects endogenous levels of CBLL1 at Human, Mouse
Immunogen: Synthesized peptide derived from human CBLL1
Function E3 ubiquitin-protein ligase that mediates ubiquitination of several tyrosine-phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation. Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing. Its function in the WMM complex is unknown.
Protein Name E3 Ubiquitin-Protein Ligase Hakai
Casitas B-Lineage Lymphoma-Transforming Sequence-Like Protein 1
C-Cbl-Like Protein 1
Ring Finger Protein 188
Ring-Type E3 Ubiquitin Transferase Hakai
Database Links Reactome: R-HSA-8876493
Cellular Localisation Nucleus Speckle
Nucleus
Nucleoplasm
Cytoplasm
Mainly Nuclear With Some Fraction Located In The Cytoplasm
Zc3h13 Is Required To Anchor Component Of The Macom Subcomplex
Such As Virma
In The Nucleus
Alternative Antibody Names Anti-E3 Ubiquitin-Protein Ligase Hakai antibody
Anti-Casitas B-Lineage Lymphoma-Transforming Sequence-Like Protein 1 antibody
Anti-C-Cbl-Like Protein 1 antibody
Anti-Ring Finger Protein 188 antibody
Anti-Ring-Type E3 Ubiquitin Transferase Hakai antibody
Anti-CBLL1 antibody
Anti-HAKAI antibody
Anti-RNF188 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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