产品详情
简单介绍:
Anti-CCL25 antibody (24-150) (STJ28626)
详情介绍:
Host: | Rabbit |
Applications: | IHC |
Reactivity: | Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CCL25 (24-150) is suitable for use in Immunohistochemistry research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | IHC-P 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CCL25 |
Gene ID: | 6370 |
Uniprot ID: | CCL25_HUMAN |
Immunogen Region: | 24-150 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-150 of human CCL25 (NP_005615.2). |
Immunogen Sequence: | QGVFEDCCLAYHYPIGWAVL RRAWTYRIQEVSGSCNLPAA IFYLPKRHRKVCGNPKSREV QRAMKLLDARNKVFAKLHHN TQTFQAGPHAVKKLSSGNSK LSSSKFSNPISSSKRNVSLL ISANSGL |
Tissue Specificity | Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine. |
Function | Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
Protein Name | C-C Motif Chemokine 25 Chemokine Teck Small-Inducible Cytokine A25 Thymus-Expressed Chemokine |
Database Links | Reactome: R-HSA-380108 Reactome: R-HSA-418594 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-C-C Motif Chemokine 25 antibody Anti-Chemokine Teck antibody Anti-Small-Inducible Cytokine A25 antibody Anti-Thymus-Expressed Chemokine antibody Anti-CCL25 antibody Anti-SCYA25 antibody Anti-TECK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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