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  • 产品名称：Human ILK-1 (Integrin Linked Kinase 1) Sandwich ELISA Kit Ready-To-Use (STJE0016378)

  • 产品型号：STJE0016378
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human ILK-1 (Integrin Linked Kinase 1) Sandwich ELISA Kit Ready-To-Use (STJE0016378)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 33.5pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This ILK-1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: ILK
Gene ID: 3611
Uniprot ID: ILK_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity Highly expressed in heart followed by skeletal muscle, pancreas and kidney. Weakly expressed in placenta, lung and liver.
Post Translational Modifications Autophosphorylated on serine residues.
Function Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Regulates cell motility by forming a complex with PARVB. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
Protein Name Integrin-Linked Protein Kinase
59 Kda Serine/Threonine-Protein Kinase
Beta-Integrin-Linked Kinase
Ilk-1
Ilk-2
P59ilk
Database Links Reactome: R-HSA-446343
Reactome: R-HSA-446353
Cellular Localisation Cell Junction
Focal Adhesion
Cell Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Cell Projection
Lamellipodium
Cytoplasm
Myofibril
Sarcomere
Alternative ELISA Names Integrin-Linked Protein Kinase ELISA kit
59 Kda Serine/Threonine-Protein Kinase ELISA kit
Beta-Integrin-Linked Kinase ELISA kit
Ilk-1 ELISA kit
Ilk-2 ELISA kit
P59ilk ELISA kit
ILK ELISA kit
ILK1 ELISA kit
ILK2 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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