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  • 产品名称：Human IREM1 (Immune Receptor Expressed On Myeloid Cells 1) Sandwich ELISA Kit Ready-To-Use (STJE0016438)

  • 产品型号：STJE0016438
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human IREM1 (Immune Receptor Expressed On Myeloid Cells 1) Sandwich ELISA Kit Ready-To-Use (STJE0016438)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.062ng/mL
Detection Limit: 0.156-10ng/mL
Short Description: This IREM1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 3 hrs
Gene Symbol: CD300LF
Gene ID: 146722
Uniprot ID: CLM1_HUMAN
Immunogen Region: Ready-To-Use
Sample Type: tissue homogenates, cell lysates or other biological fluids.
Tissue Specificity Highly expressed in spleen, peripheral blood leukocyte and monocyte, and lung. Weakly expressed in thymus, heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary, small intestine or colon. Expressed selectively in monocytes and monocyte-related cells.
Post Translational Modifications Phosphorylated on tyrosine.
Function Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition.recognizes and binds PS as a ligand which is expressed on the surface of apoptotic cells. Plays an important role in the maintenance of immune homeostasis, by promoting macrophage-mediated efferocytosis and by inhibiting dendritic cell-mediated efferocytosis. Negatively regulates Fc epsilon receptor-dependent mast cell activation and allergic responses via binding to ceramide and sphingomyelin which act as ligands. May act as a coreceptor for interleukin 4 (IL-4). Associates with and regulates IL-4 receptor alpha-mediated responses by augmenting IL-4- and IL-13-induced signaling. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 and TRIF through activation of PTPN6/SHP-1 and PTPN11/SHP-2. Inhibits osteoclast formation. Induces macrophage cell death upon engagement.
Protein Name Cmrf35-Like Molecule 1
Clm-1
Cd300 Antigen-Like Family Member F
Immune Receptor Expressed On Myeloid Cells 1
Irem-1
Immunoglobulin Superfamily Member 13
Igsf13
Nk Inhibitory Receptor
Cd Antigen Cd300f
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative ELISA Names Cmrf35-Like Molecule 1 ELISA kit
Clm-1 ELISA kit
Cd300 Antigen-Like Family Member F ELISA kit
Immune Receptor Expressed On Myeloid Cells 1 ELISA kit
Irem-1 ELISA kit
Immunoglobulin Superfamily Member 13 ELISA kit
Igsf13 ELISA kit
Nk Inhibitory Receptor ELISA kit
Cd Antigen Cd300f ELISA kit
CD300LF ELISA kit
CD300F ELISA kit
CLM1 ELISA kit
IGSF13 ELISA kit
IREM1 ELISA kit
NKIR ELISA kit
UNQ3105 ELISA kit
PRO10111 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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