产品详情
简单介绍:
Anti-CCR3 antibody (1-50) (STJ500402)
详情介绍:
Host: | Rabbit |
Applications: | ELISA/IHC/IP/WB |
Reactivity: | Human/Monkey |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CCR3 (1-50) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.60-0.70 µg/µl |
Dilution Range: | WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:200 IHC: 1:100 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | CCR3 |
Gene ID: | 1232 |
Uniprot ID: | CCR3_HUMAN |
Immunogen Region: | 1-50 |
Immunogen: | Synthetic peptide taken within amino acid region 1-50 on human CCR3 protein. |
Tissue Specificity | In eosinophils as well as trace amounts in neutrophils and monocytes. |
Function | Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1. (Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection. |
Protein Name | C-C Chemokine Receptor Type 3 C C Ckr3 C-C Ckr-3 Cc-Ckr-3 Ccr-3 Ccr3 Ckr 3 Ckr3 Eosinophil Eotaxin Receptor Cd Antigen Cd193 |
Database Links | Reactome: R-HSA-380108 Reactome: R-HSA-418594 |
Cellular Localisation | Cell Membrane Multi-Pass Membrane Protein |
Alternative Antibody Names | Anti-C-C Chemokine Receptor Type 3 antibody Anti-C C Ckr3 antibody Anti-C-C Ckr-3 antibody Anti-Cc-Ckr-3 antibody Anti-Ccr-3 antibody Anti-Ccr3 antibody Anti-Ckr 3 antibody Anti-Ckr3 antibody Anti-Eosinophil Eotaxin Receptor antibody Anti-Cd Antigen Cd193 antibody Anti-CCR3 antibody Anti-CMKBR3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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