产品详情
简单介绍:
Anti-BAHD1 antibody (214-264 aa) (STJ194263)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Bromo adjacent homology domain-containing 1 protein (214-264 aa) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | BAHD1 |
Gene ID: | 22893 |
Uniprot ID: | BAHD1_HUMAN |
Immunogen Region: | 214-264 aa |
Specificity: | This antibody detects endogenous levels of BAHD1 at Human/Mouse |
Immunogen: | Synthesized peptide derived from the human BAHD1 at the amino acid range 214-264 |
Function | Heterochromatin protein that acts as a transcription repressor and has the ability to promote the formation of large heterochromatic domains. May act by recruiting heterochromatin proteins such as CBX5 (HP1 alpha), HDAC5 and MBD1. Represses IGF2 expression by binding to its CpG-rich P3 promoter and recruiting heterochromatin proteins. At specific stages of Listeria infection, in complex with TRIM28, corepresses interferon-stimulated genes, including IFNL1, IFNL2 and IFNL3. |
Protein Name | Bromo Adjacent Homology Domain-Containing 1 Protein Bah Domain-Containing Protein 1 |
Cellular Localisation | Nucleus Chromosome Localizes To Heterochromatin And Inactive X Chromosome Colocalizes With Histone H3 Trimethylated At 'Lys-27' (H3k27me3) |
Alternative Antibody Names | Anti-Bromo Adjacent Homology Domain-Containing 1 Protein antibody Anti-Bah Domain-Containing Protein 1 antibody Anti-BAHD1 antibody Anti-KIAA0945 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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