产品详情
简单介绍:
Human KIF5A (Kinesin Family, Member 5A) Sandwich ELISA Kit (STJE0010155)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.118ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This KIF5A Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | KIF5A |
Gene ID: | 3798 |
Uniprot ID: | KIF5A_HUMAN |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Tissue Specificity | Distributed throughout the CNS but is highly enriched in subsets of neurons. |
Post Translational Modifications | |
Function | Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. |
Protein Name | Kinesin Heavy Chain Isoform 5a Kinesin Heavy Chain Neuron-Specific 1 Neuronal Kinesin Heavy Chain Nkhc |
Database Links | Reactome: R-HSA-2132295 Reactome: R-HSA-264876 Reactome: R-HSA-5625970 Reactome: R-HSA-6811434 Reactome: R-HSA-983189 |
Cellular Localisation | Cytoplasm Perinuclear Region Cytoskeleton Perikaryon Concentrated In The Cell Body Of The Neurons Particularly In The Perinuclear Region |
Alternative ELISA Names | Kinesin Heavy Chain Isoform 5a ELISA kit Kinesin Heavy Chain Neuron-Specific 1 ELISA kit Neuronal Kinesin Heavy Chain ELISA kit Nkhc ELISA kit KIF5A ELISA kit NKHC1 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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