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  • 产品名称：Human KIF5B (Kinesin Family, Member 5B) Sandwich ELISA Kit (STJE0010156)

  • 产品型号：STJE0010156
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human KIF5B (Kinesin Family, Member 5B) Sandwich ELISA Kit (STJE0010156)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 27.8pg/mL
Detection Limit: 78.1-5000pg/mL
Short Description: This KIF5B Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: KIF5B
Gene ID: 3799
Uniprot ID: KINH_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation. Through binding with PLEKHM2 and ARL8B, directs lysosome movement toward microtubule plus ends (Probable). Involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells.
Protein Name Kinesin-1 Heavy Chain
Conventional Kinesin Heavy Chain
Ubiquitous Kinesin Heavy Chain
Ukhc
Database Links Reactome: R-HSA-2132295
Reactome: R-HSA-264876
Reactome: R-HSA-5625970
Reactome: R-HSA-6811434
Reactome: R-HSA-9725370
Reactome: R-HSA-9725371
Reactome: R-HSA-983189
Cellular Localisation Cytoplasm
Cytoskeleton
Cytolytic Granule Membrane
Lysosome Membrane
Peripheral Membrane Protein
Cytoplasmic Side
Uniformly Distributed Between Soma And Neurites In Hippocampal Neurons
Alternative ELISA Names Kinesin-1 Heavy Chain ELISA kit
Conventional Kinesin Heavy Chain ELISA kit
Ubiquitous Kinesin Heavy Chain ELISA kit
Ukhc ELISA kit
KIF5B ELISA kit
KNS ELISA kit
KNS1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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