产品详情
简单介绍:
Anti-CD108 antibody [MEM-150] (STJ16100094)
详情介绍:
Host: | Mouse |
Applications: | FC/IP/WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-CD108 is suitable for use in Flow Cytometry, Immunoprecipitation and Western Blot research applications. |
Clonality: | Monoclonal |
Clone ID: | MEM-150 |
Conjugation: | Unconjugated |
Isotype: | IgM |
Formulation: | Tris buffered saline (TBS) solution with 15 mM sodium azide |
Concentration: | 1 mg/mL |
Storage Instruction: | Store at 2-8°C upon receipt. |
Gene Symbol: | SEMA7A |
Gene ID: | 8482 |
Uniprot ID: | SEM7A_HUMAN |
Immunogen: | HPB-ALL human T cell line |
Tissue Specificity | Detected in skin keratinocytes and on endothelial cells from skin blood vessels (at protein level). Expressed in fibroblasts, keratinocytes, melanocytes, placenta, testis, ovary, spleen, brain, spinal chord, lung, heart, adrenal gland, lymph nodes, thymus, intestine and kidney. |
Function | Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of pro-inflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes. |
Protein Name | Semaphorin-7a Cdw108 Jmh Blood Group Antigen John-Milton-Hargen Human Blood Group Ag Semaphorin-K1 Sema K1 Semaphorin-L Sema L Cd Antigen Cd108 |
Database Links | Reactome: R-HSA-416700 |
Cellular Localisation | Cell Membrane Lipid-Anchor Gpi-Anchor Extracellular Side Detected In A Punctate Pattern On The Cell Membrane Of Basal And Supra-Basal Skin Keratinocytes |
Alternative Antibody Names | Anti-Semaphorin-7a antibody Anti-Cdw108 antibody Anti-Jmh Blood Group Antigen antibody Anti-John-Milton-Hargen Human Blood Group Ag antibody Anti-Semaphorin-K1 antibody Anti-Sema K1 antibody Anti-Semaphorin-L antibody Anti-Sema L antibody Anti-Cd Antigen Cd108 antibody Anti-SEMA7A antibody Anti-CD108 antibody Anti-SEMAL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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