产品详情
简单介绍：
Anti-BAZ1A antibody (736-786 aa) (STJ195028)
详情介绍：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Bromodomain adjacent to zinc finger domain protein 1A (736-786 aa) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | BAZ1A |
| Gene ID: | 11177 |
| Uniprot ID: | BAZ1A_HUMAN |
| Immunogen Region: | 736-786 aa |
| Specificity: | This antibody detects endogenous levels of BAZ1A at Human/Mouse |
| Immunogen: | Synthesized peptide derived from the human BAZ1A at the amino acid range 736-786 |
| Function | Regulatory subunit of the ATP-dependent ACF-1 and ACF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and slide edge- and center-positioned histone octamers away from their original location on the DNA template to facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template in an ATP-dependent manner. The ACF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the ACF-5 ISWI chromatin remodeling complex. Has a role in sensing the length of DNA which flank nucleosomes, which modulates the nucleosome spacing activity of the ACF-5 ISWI chromatin remodeling complex. Involved in DNA replication and together with SMARCA5/SNF2H is required for replication of pericentric heterochromatin in S-phase. May have a role in nuclear receptor-mediated transcription repression. |
| Protein Name | Bromodomain Adjacent To Zinc Finger Domain Protein 1a Atp-Dependent Chromatin-Remodeling Protein Atp-Utilizing Chromatin Assembly And Remodeling Factor 1 Hacf1 Chrac Subunit Acf1 Williams Syndrome Transcription Factor-Related Chromatin-Remodeling Factor 180 Wcrf180 Hwalp1 |
| Cellular Localisation | Nucleus Localizes To Pericentric Heterochromatin May Target The Chrac Complex To Heterochromatin Localizes To Sites Of Dna Damage |
| Alternative Antibody Names | Anti-Bromodomain Adjacent To Zinc Finger Domain Protein 1a antibody Anti-Atp-Dependent Chromatin-Remodeling Protein antibody Anti-Atp-Utilizing Chromatin Assembly And Remodeling Factor 1 antibody Anti-Hacf1 antibody Anti-Chrac Subunit Acf1 antibody Anti-Williams Syndrome Transcription Factor-Related Chromatin-Remodeling Factor 180 antibody Anti-Wcrf180 antibody Anti-Hwalp1 antibody Anti-BAZ1A antibody Anti-ACF1 antibody Anti-WCRF180 antibody Anti-HSPC317 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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