产品详情
简单介绍:
Human LTBR (Tumor necrosis factor receptor superfamily member 3) CLIA Kit (STJC0000253)
详情介绍:
Applications: | CLIA |
Reactivity: | Human |
Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Sensitivity: | 37.5pg/mL |
Detection Limit: | 62.5~4000pg/mL |
Short Description: | This human LTBR kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes. |
Storage Instruction: | If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual. |
Assay Time: | 3.5h |
Detection: | Chemiluminescence |
Gene Symbol: | LTBR |
Gene ID: | 4055 |
Uniprot ID: | TNR3_HUMAN |
Specificity: | This kit recognizes Human LT Beta R in samples. No significant cross-reactivity or interference between Human LT Beta R and analogues was observed. |
Sample Type: | Serum, plasma and other biological fluids |
Function | Receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. Promotes apoptosis via TRAF3 and TRAF5. May play a role in the development of lymphoid organs. |
Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 3 Lymphotoxin-Beta Receptor Tumor Necrosis Factor C Receptor Tumor Necrosis Factor Receptor 2-Related Protein Tumor Necrosis Factor Receptor Type Iii Tnf-Riii Tnfr-Iii |
Database Links | Reactome: R-HSA-5668541 Reactome: R-HSA-5676594 |
Cellular Localisation | Membrane Single-Pass Type I Membrane Protein |
Alternative CLIA Names | Tumor Necrosis Factor Receptor Superfamily Member 3 CLIA kit Lymphotoxin-Beta Receptor CLIA kit Tumor Necrosis Factor C Receptor CLIA kit Tumor Necrosis Factor Receptor 2-Related Protein CLIA kit Tumor Necrosis Factor Receptor Type Iii CLIA kit Tnf-Riii CLIA kit Tnfr-Iii CLIA kit LTBR CLIA kit D12S370 CLIA kit TNFCR CLIA kit TNFR3 CLIA kit TNFRSF3 CLIA kit |
Specificity | This kit recognizes Human LTβR in samples. No significant cross-reactivity or interference between Human LTβR and analogues was observed. |
Reproducibility | Both intra-CV and inter-CV are |
Information sourced from Uniprot.org
Item Specifications Storage
Micro CLIA Plate (Dismountable) | 96T: 8 wells ×12 strips strips | -20℃, 6 months |
Reference Standard | 96T: 2 vials 48T: 1 vial | -20℃, 6 months |
Concentrated Biotinylated Detection Ab (100×) | 96T: 1 vial, 120 μL 60 μL | -20℃, 6 months |
Concentrated HRP Conjugate (100×) | 96T: 1 vial, 120 μL 60 μL | -20℃ (Protect from light), 6 months |
Reference Standard & Sample Diluent | 1 vial, 20 mL | 2-8°C, 6 months |
Biotinylated Detection Ab Diluent | 1 vial, 14 mL | 2-8°C, 6 months |
HRP Conjugate Diluent | 1 vial, 14 mL | 2-8°C, 6 months |
Concentrated Wash Buffer (25×) | 1 vial, 30 mL | 2-8°C, 6 months |
Substrate Reagent A | 1 vial, 5 mL | 2-8℃ (Protect from light) |
Substrate Reagent B | 1 vial, 5 mL | 2-8℃ (Protect from light) |
Plate Sealer | 5 pieces | |
Manual | 1 copy | |
Certificate of Analysis | 1 copy |
Sample Type Range (%) Average Recovery (%)
Serum(n=8) | 85-96 | 91 |
EDTA plasma(n=8) | 99-116 | 108 |
Cell culture media(n=8) | 86-98 | 93 |
Intra-assay Precision Intra-assay Precision Intra-assay Precision Inter-assay Precision Inter-assay Precision Inter-assay Precision
Sample | 1.00 | 2.00 | 3.00 | 1.00 | 2.00 | 3.00 |
n | 20.00 | 20.00 | 20.00 | 20.00 | 20.00 | 20.00 |
Mean (pg/mL) | 195.26 | 403.94 | 1376.58 | 195.96 | 386.93 | 1413.13 |
Standard deviation | 21.09 | 36.19 | 89.62 | 17.17 | 30.53 | 153.47 |
CV (%) | 10.80 | 8.96 | 6.51 | 8.76 | 7.89 | 10.86 |
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