产品详情
简单介绍:
Anti-BFSP1 antibody (494-544 aa) (STJ194815)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Filensin (494-544 aa) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | BFSP1 |
Gene ID: | 631 |
Uniprot ID: | BFSP1_HUMAN |
Immunogen Region: | 494-544 aa |
Specificity: | This antibody detects endogenous levels of BFSP1 at Human/Mouse/Rat |
Immunogen: | Synthesized peptide derived from the human BFSP1 at the amino acid range 494-544 |
Post Translational Modifications | Proteolytically cleaved during lens cell fiber differentiation with increased fragmentation as fiber cell age increases. Filensin C-terminal fragment: Myristoylated at Gly-434 following proteolytic cleavage at Asp-433. Filensin N-terminal fragment: Acetylated at Ala-42 following proteolytic cleavage at Leu-41. |
Function | Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA. Involved in altering the calcium regulation of MIP water permeability. |
Protein Name | Filensin Beaded Filament Structural Protein 1 Lens Fiber Cell Beaded-Filament Structural Protein Cp 115 Cp115 Lens Intermediate Filament-Like Heavy Lifl-H Cleaved Into - Filensin C-Terminal Fragment - Filensin N-Terminal Fragment |
Cellular Localisation | Cell Membrane Peripheral Membrane Protein Cytoplasmic Side Cytoplasm Cytoskeleton Cell Cortex |
Alternative Antibody Names | Anti-Filensin antibody Anti-Beaded Filament Structural Protein 1 antibody Anti-Lens Fiber Cell Beaded-Filament Structural Protein Cp 115 antibody Anti-Cp115 antibody Anti-Lens Intermediate Filament-Like Heavy antibody Anti-Lifl-H Cleaved Into - Filensin C-Terminal Fragment - Filensin N-Terminal Fragment antibody Anti-BFSP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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