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  • 产品名称：Anti-CD28 antibody [204-12] (STJ16102563)

  • 产品型号：STJ16102563
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CD28 antibody [204-12] (STJ16102563)
详情介绍：
Host: Mouse
Applications: FC/FUNC/IF/IHC
Reactivity: Cow/Human/Mouse/Pig/Sheep
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-CD28 is suitable for use in Flow Cytometry, FUNC, Immunofluorescence and Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: 204-12
Conjugation: Unconjugated
Isotype: IgG2bk
Formulation: PBS with 0.02% Sodium Azide.
Purification: Affinity purified from tissue culture.
Concentration: Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL.
Dilution Range: Flow cytometry (0, 5-1, 0 µg/million cells in 0, 1 ml). Functional studies (0, 02-2, 0 µg/ml without azide). Immunofluorescence (0, 5-1, 0 µg/ml). Immunohistology (1-2 µg/ml for 30-60 min at RT; for staining of formalin-fixed tissues no suitable anti
Storage Instruction: Store for up to 1 year at 2-8°C upon receipt.
Gene Symbol: CD28
Gene ID: 940
Uniprot ID: CD28_HUMAN
Immunogen: A BALB/c mouse was immunized with human leucocytes. Fusion partner: NS-1.
Post Translational Modifications CD40LG induces tyrosine phosphorylation of isoform 3.
Function Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation. Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells.
Protein Name T-Cell-Specific Surface Glycoprotein Cd28
Tp44
Cd Antigen Cd28
Database Links Reactome: R-HSA-1257604
Reactome: R-HSA-164939
Reactome: R-HSA-2219530
Reactome: R-HSA-389356
Reactome: R-HSA-389357
Reactome: R-HSA-389359
Reactome: R-HSA-6811558
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Isoform 3: Cell Surface
Alternative Antibody Names Anti-T-Cell-Specific Surface Glycoprotein Cd28 antibody
Anti-Tp44 antibody
Anti-Cd Antigen Cd28 antibody
Anti-CD28 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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