产品详情
简单介绍:
Anti-CD300A antibody (141-190 aa) (STJ98999)
详情介绍:
Host: | Rabbit |
Applications: | IHC/IF/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-CMRF35-like molecule 8 (141-190 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | IHC-P 1:50-200 ELISA 1:10000-20000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CD300A |
Gene ID: | 11314 |
Uniprot ID: | CLM8_HUMAN |
Immunogen Region: | 141-190 aa |
Specificity: | The antibody detects endogenous CD300a |
Immunogen: | Synthetic peptide from the human protein at the amino acid range 141-190 |
Post Translational Modifications | Phosphorylated on tyrosine. N-glycosylated. |
Function | Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6. |
Protein Name | Cmrf35-Like Molecule 8 Clm-8 Cd300 Antigen-Like Family Member A Cmrf-35-H9 Cmrf35-H9 Cmrf35-H Irc1/Irc2 Immunoglobulin Superfamily Member 12 Igsf12 Inhibitory Receptor Protein 60 Irp60 Nk Inhibitory Receptor Cd Antigen Cd300a |
Database Links | Reactome: R-HSA-198933 Reactome: R-HSA-6798695 |
Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein |
Alternative Antibody Names | Anti-Cmrf35-Like Molecule 8 antibody Anti-Clm-8 antibody Anti-Cd300 Antigen-Like Family Member A antibody Anti-Cmrf-35-H9 antibody Anti-Cmrf35-H9 antibody Anti-Cmrf35-H antibody Anti-Irc1/Irc2 antibody Anti-Immunoglobulin Superfamily Member 12 antibody Anti-Igsf12 antibody Anti-Inhibitory Receptor Protein 60 antibody Anti-Irp60 antibody Anti-Nk Inhibitory Receptor antibody Anti-Cd Antigen Cd300a antibody Anti-CD300A antibody Anti-CMRF35H antibody Anti-IGSF12 antibody Anti-HSPC083 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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