产品详情
查看大图

  • 产品名称：Anti-BNIP1 antibody (Internal) (STJ71277)

  • 产品型号：STJ71277-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
你添加了1件商品 查看购物车
简单介绍：
Anti-BNIP1 antibody (Internal) (STJ71277)
详情介绍：
Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-BNIP1 (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-0.5-1.5µg/ml
ELISA-antibody detection limit dilution 1:8000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: BNIP1
Gene ID: 662
Uniprot ID: SEC20_HUMAN
Immunogen Region: Internal
Accession Number: NP_001196.1; NP_053581.1; NP_053582.1; NP_053583.1
Specificity: All reported variants represent isoform 1 (NP_001196.1; NP_053581.1; NP_053582.1; NP_053583.1)
Immunogen Sequence: DLLRQRKTTKESLAQ
Post Translational Modifications Polyubiquitinated. 'Lys-63'-linked polyubiquitination by RNF185 increases the interaction with the autophagy receptor SQSTM1. Undergoes 'Lys-29'- and 'Lys-63'-linked polyubiquitination by RNF186 that may regulate BNIP1 localization to the mitochondrion.
Function As part of a SNARE complex may be involved in endoplasmic reticulum membranes fusion and be required for the maintenance of endoplasmic reticulum organization. Also plays a role in apoptosis. It is for instance required for endoplasmic reticulum stress-induced apoptosis. As a substrate of RNF185 interacting with SQSTM1, might also be involved in mitochondrial autophagy (Probable).
Protein Name Vesicle Transport Protein Sec20
Bcl2/Adenovirus E1b 19 Kda Protein-Interacting Protein 1
Transformation-Related Gene 8 Protein
Trg-8
Database Links Reactome: R-HSA-6811434
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Iv Membrane Protein
Mitochondrion Membrane
Localization To The Mitochondrion Is Regulated By Rnf186
Alternative Antibody Names Anti-Vesicle Transport Protein Sec20 antibody
Anti-Bcl2/Adenovirus E1b 19 Kda Protein-Interacting Protein 1 antibody
Anti-Transformation-Related Gene 8 Protein antibody
Anti-Trg-8 antibody
Anti-BNIP1 antibody
Anti-NIP1 antibody
Anti-SEC20L antibody
Anti-TRG8 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
姓名：
电话：
您的需求：
 

沪公网安备 31011002002624号