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  • 产品名称：Human NEU (Neuraminidase) Sandwich ELISA Kit (STJE0010928)

  • 产品型号：STJE0010928
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human NEU (Neuraminidase) Sandwich ELISA Kit (STJE0010928)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.126ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This NEU Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: NEU1
Gene ID: 4758
Uniprot ID: NEUR1_HUMAN
Sample Type: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Tissue Specificity Highly expressed in pancreas, followed by skeletal muscle, kidney, placenta, heart, lung and liver. Weakly expressed in brain.
Post Translational Modifications N-glycosylated. Phosphorylation of tyrosine within the internalization signal results in inhibition of sialidase internalization and blockage on the plasma membrane.
Function Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex. Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage.
Protein Name Sialidase-1
Acetylneuraminyl Hydrolase
G9 Sialidase
Lysosomal Sialidase
N-Acetyl-Alpha-Neuraminidase 1
Database Links Reactome: R-HSA-1660662
Reactome: R-HSA-4085001
Reactome: R-HSA-4341670
Reactome: R-HSA-6798695
Cellular Localisation Lysosome Membrane
Peripheral Membrane Protein
Lumenal Side
Lysosome Lumen
Cell Membrane
Cytoplasmic Vesicle
Lysosome
Localized Not Only On The Inner Side Of The Lysosomal Membrane And In The Lysosomal Lumen
But Also On The Plasma Membrane And In Intracellular Vesicles
Alternative ELISA Names Sialidase-1 ELISA kit
Acetylneuraminyl Hydrolase ELISA kit
G9 Sialidase ELISA kit
Lysosomal Sialidase ELISA kit
N-Acetyl-Alpha-Neuraminidase 1 ELISA kit
NEU1 ELISA kit
NANH ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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