产品详情
简单介绍:
Anti-BTBD7 antibody (1050-1150) (STJ500297)
详情介绍:
Host: | Rabbit |
Applications: | CM/ELISA/ICC/IF/IHC/IP/WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-BTBD7 (1050-1150) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Purification: | Affinity Purified |
Concentration: | 0.61-0.68 µg/µl |
Dilution Range: | WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:200 IHC: 1:200 ICC: 1:200 CFM: 1:200 |
Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Gene Symbol: | BTBD7 |
Gene ID: | 55727 |
Uniprot ID: | BTBD7_HUMAN |
Immunogen Region: | 1050-1150 |
Immunogen: | Synthetic peptide taken within amino acid region 1050-1150 on human BTBD7 protein. |
Function | Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. |
Protein Name | Btb/Poz Domain-Containing Protein 7 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Btb/Poz Domain-Containing Protein 7 antibody Anti-BTBD7 antibody Anti-KIAA1525 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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