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  • 产品名称：Human OXCT1 (3-Oxoacid Coenzyme A Transferase 1) Sandwich ELISA Kit (STJE0011227)

  • 产品型号：STJE0011227
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human OXCT1 (3-Oxoacid Coenzyme A Transferase 1) Sandwich ELISA Kit (STJE0011227)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 0.124ng/mL
Detection Limit: 0.312-20ng/mL
Short Description: This OXCT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: OXCT1
Gene ID: 5019
Uniprot ID: SCOT1_HUMAN
Sample Type: tissue homogenates or other biological fluids.
Tissue Specificity Abundant in heart, followed in order by brain, kidney, skeletal muscle, and lung, whereas in liver it is undetectable. Expressed (at protein level) in all tissues (except in liver), most abundant in myocardium, then brain, kidney, adrenal glands, skeletal muscle and lung.also detectable in leukocytes and fibroblasts.
Post Translational Modifications
Function Key enzyme for ketone body catabolism. Catalyzes the first, rate-limiting step of ketone body utilization in extrahepatic tissues, by transferring coenzyme A (CoA) from a donor thiolester species (succinyl-CoA) to an acceptor carboxylate (acetoacetate), and produces acetoacetyl-CoA. Acetoacetyl-CoA is further metabolized by acetoacetyl-CoA thiolase into two acetyl-CoA molecules which enter the citric acid cycle for energy production. Forms a dimeric enzyme where both of the subunits are able to form enzyme-CoA thiolester intermediates, but only one subunit is competent to transfer the CoA moiety to the acceptor carboxylate (3-oxo acid) and produce a new acyl-CoA. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
Protein Name Succinyl-Coa -3-Ketoacid Coenzyme A Transferase 1 - Mitochondrial
Scot
3-Oxoacid Coa-Transferase 1
Somatic-Type Succinyl-Coa -3-Oxoacid Coa-Transferase
Scot-S
Succinyl-Coa -3-Oxoacid Coa Transferase
Database Links Reactome: R-HSA-77108
Cellular Localisation Mitochondrion
Alternative ELISA Names Succinyl-Coa -3-Ketoacid Coenzyme A Transferase 1 - Mitochondrial ELISA kit
Scot ELISA kit
3-Oxoacid Coa-Transferase 1 ELISA kit
Somatic-Type Succinyl-Coa -3-Oxoacid Coa-Transferase ELISA kit
Scot-S ELISA kit
Succinyl-Coa -3-Oxoacid Coa Transferase ELISA kit
OXCT1 ELISA kit
OXCT ELISA kit
SCOT ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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