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  • 产品名称：Human PAEP (Progestagen Associated Endometrial Protein) Sandwich ELISA Kit (STJE0011248)

  • 产品型号：STJE0011248
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Human PAEP (Progestagen Associated Endometrial Protein) Sandwich ELISA Kit (STJE0011248)
详情介绍：
Applications: ELISA
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity: 1.8ng/mL
Detection Limit: 4.68-300ng/mL
Short Description: This PAEP Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
Storage Instruction: Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time: 4.5 hrs
Gene Symbol: PAEP
Gene ID: 5047
Uniprot ID: PAEP_HUMAN
Sample Type: serum, plasma, tissue homogenates or other biological fluids.
Tissue Specificity This protein is, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. Glycodelin-A is expressed in amniotic fluid, endometrium/decidua and maternal serum (at protein level). Glycodelin-F is expressed in follicular fluid, luteinized granulosa cells and the oviduct (at protein level). Glycodelin-S is expressed in seminal plasma and seminal vesicles (at protein level). Glycodelin-C is detected in cumulus cells (at protein level), but cumulus cells do not synthesize Glycodelin-C but take up and convert glycodelin-A and -F vis glycan remodeling.
Post Translational Modifications Four distinct glycoforms A, C, F and S arise from different N-linked oligosaccharide chains at amino acid residues Asn-46 and Asn-81. Glycodelin-A and -F are taken up by the cumulus cells in which partial deglycosylation takes place to produce glycodelin-C.
Function Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities. Glycodelin-C stimulates binding of spermatozoa to the zona pellucida. Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa. Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa.
Protein Name Glycodelin
Gd
Placental Protein 14
Pp14
Pregnancy-Associated Endometrial Alpha-2 Globulin
Paeg
Peg
Progestagen-Associated Endometrial Protein
Progesterone-Associated Endometrial Protein
Zona-Binding Inhibitory Factor-1
Zif-1
Database Links
Cellular Localisation Secreted
Alternative ELISA Names Glycodelin ELISA kit
Gd ELISA kit
Placental Protein 14 ELISA kit
Pp14 ELISA kit
Pregnancy-Associated Endometrial Alpha-2 Globulin ELISA kit
Paeg ELISA kit
Peg ELISA kit
Progestagen-Associated Endometrial Protein ELISA kit
Progesterone-Associated Endometrial Protein ELISA kit
Zona-Binding Inhibitory Factor-1 ELISA kit
Zif-1 ELISA kit
PAEP ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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