产品详情
简单介绍:
Human PANK4 (Pantothenate Kinase 4) Sandwich ELISA Kit Ready-To-Use (STJE0017654)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.064ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This PANK4 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | PANK4 |
Gene ID: | 55229 |
Uniprot ID: | PANK4_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | tissue homogenates or other biological fluids. |
Tissue Specificity | Widely expressed with high expression in the muscle. Expressed in the retina and lens epithelium, mainly in ganglion cell layer, outer plexiform layer and retinal pigment layer (at protein level). |
Post Translational Modifications | |
Function | Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein. May play a role in the physiological regulation of CoA intracellular levels (Probable). |
Protein Name | 4'-Phosphopantetheine Phosphatase Inactive Pantothenic Acid Kinase 4 Hpank4 |
Database Links | Reactome: R-HSA-196783 |
Cellular Localisation | Cytoplasm |
Alternative ELISA Names | 4'-Phosphopantetheine Phosphatase ELISA kit Inactive Pantothenic Acid Kinase 4 ELISA kit Hpank4 ELISA kit PANK4 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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