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  • 产品名称：Anti-CD55 antibody (241-290 aa) (STJ96615)

  • 产品型号：STJ96615
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CD55 antibody (241-290 aa) (STJ96615)
详情介绍：
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Complement decay-accelerating factor (241-290 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CD55
Gene ID: 1604
Uniprot ID: DAF_HUMAN
Immunogen Region: 241-290 aa
Specificity: CD55 Polyclonal Antibody detects endogenous levels of CD55 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD55 at the amino acid range 241-290
Post Translational Modifications The Ser/Thr-rich domain is heavily O-glycosylated.
Function This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Inhibits complement activation by destabilizing and preventing the formation of C3 and C5 convertases, which prevents complement damage. (Microbial infection) Acts as a receptor for Coxsackievirus A21, coxsackieviruses B1, B3 and B5. (Microbial infection) Acts as a receptor for Human enterovirus 70 and D68 (Probable). (Microbial infection) Acts as a receptor for Human echoviruses 6, 7, 11, 12, 20 and 21.
Protein Name Complement Decay-Accelerating Factor
Cd Antigen Cd55
Database Links Reactome: R-HSA-373080
Reactome: R-HSA-6798695
Reactome: R-HSA-6807878
Reactome: R-HSA-977606
Cellular Localisation Isoform 1: Cell Membrane
Single-Pass Type I Membrane Protein
Isoform 2: Cell Membrane
Lipid-Anchor
Gpi-Anchor
Isoform 3: Secreted
Isoform 4: Secreted
Isoform 5: Secreted
Isoform 6: Cell Membrane
Isoform 7: Cell Membrane
Alternative Antibody Names Anti-Complement Decay-Accelerating Factor antibody
Anti-Cd Antigen Cd55 antibody
Anti-CD55 antibody
Anti-CR antibody
Anti-DAF antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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