产品详情
简单介绍:
Anti-C11orf30 antibody (1153-1322) (STJ115602)
详情介绍:
Host: | Rabbit |
Applications: | WB/IF |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-C11orf30 (1153-1322) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 IF/ICC 1:50-1:200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | EMSY |
Gene ID: | 56946 |
Uniprot ID: | EMSY_HUMAN |
Immunogen Region: | 1153-1322 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1153-1322 of human C11orf30 (NP_064578.2). |
Immunogen Sequence: | SLMEAQIDTNVEHMIVDPPK KALATSMLTGEAGSLPSTHM VVAGMANSTPQQQKCRESCS SPSTVGSSLTTRKIDPPAVP ATGQFMRIQNVGQKKAEESP AEIIIQAIPQYAIPCHSSSN VVVEPSGLLELNNFTSQQLD DEETAMEQDIDSSTEDGTEP SPSQSSAERS |
Post Translational Modifications | O-glycosylated during cytokinesis at sites identical or close to phosphorylation sites, this interferes with the phosphorylation status. |
Function | Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. Mediates ligand-dependent transcriptional activation by nuclear hormone receptors. |
Protein Name | Brca2-Interacting Transcriptional Repressor Emsy |
Cellular Localisation | Nucleus Localizes To Dna Damage Markers In Irradiated Cells Suggesting That It Participates In Dna Repair Process |
Alternative Antibody Names | Anti-Brca2-Interacting Transcriptional Repressor Emsy antibody Anti-EMSY antibody Anti-C11orf30 antibody Anti-GL002 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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