产品详情
简单介绍:
Human PLAA (Phospholipase A2 Activating Protein) Sandwich ELISA Kit (STJE0011535)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.114ng/mL |
Detection Limit: | 0.312-20ng/mL |
Short Description: | This PLAA Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | PLAA |
Gene ID: | 9373 |
Uniprot ID: | PLAP_HUMAN |
Sample Type: | serum, plasma or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | |
Function | Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF-alpha)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis. |
Protein Name | Phospholipase A-2-Activating Protein Pla2p Plap |
Database Links | |
Cellular Localisation | Nucleus Cytoplasm Synapse Recruited To Damaged Lysosomes Decorated With K48-Linked Ubiquitin Chains |
Alternative ELISA Names | Phospholipase A-2-Activating Protein ELISA kit Pla2p ELISA kit Plap ELISA kit PLAA ELISA kit PLAP ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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