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  • 产品名称：Anti-CABP1 antibody (STJ197424)

  • 产品型号：STJ197424
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CABP1 antibody (STJ197424)
详情介绍：
Host: Rabbit
Applications: WB/IHC/IF
Reactivity: Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Calcium-binding protein 1 is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CABP1
Gene ID: 9478
Uniprot ID: CABP1_HUMAN
Specificity: The antibody detects endogenous CABP protein
Immunogen: Synthetic Peptide of CABP
Post Translational Modifications Phosphorylated. The phosphorylation regulates the activity.
Function Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function. Suppresses the calcium-dependent inactivation of CACNA1D. Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina.
Protein Name Calcium-Binding Protein 1
Cabp1
Calbrain
Caldendrin
Database Links Reactome: R-HSA-9662360
Cellular Localisation Cytoplasm
Cytoskeleton
Perinuclear Region
Cell Membrane
Lipid-Anchor
Cytoplasmic Side
Golgi Apparatus
Postsynaptic Density
L-Cabp1 Is Associated Most Likely With The Cytoskeletal Structures
Whereas S-Cabp1 Is Localized At Or Near The Plasma Membrane
Isoform L-Cabp1: Cytoplasm
Isoform S-Cabp1: Cytoplasm
Cell Cortex
S-Cabp1 Is Localized At Or Near The Plasma Membrane
Alternative Antibody Names Anti-Calcium-Binding Protein 1 antibody
Anti-Cabp1 antibody
Anti-Calbrain antibody
Anti-Caldendrin antibody
Anti-CABP1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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