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  • 产品名称：Anti-CACNA1G antibody (Internal) (STJ72033)

  • 产品型号：STJ72033-100
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CACNA1G antibody (Internal) (STJ72033)
详情介绍：
Host: Goat
Applications: Pep-ELISA
Reactivity: Human/Rat/Dog/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-CACNA1G (Internal) is suitable for use in ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: ELISA-antibody detection limit dilution 1:32000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: CACNA1G
Gene ID: 8913
Uniprot ID: CAC1G_HUMAN
Immunogen Region: Internal
Accession Number: NP_061496.2, NP_938192.1, NP_938194.1, NP_938198.1, NP_938199.1, NP_938200.1, NP_938407.1
Specificity: This antibody is expected to recognize isoform 1 (NP_061496.2) , 4 (NP_938199.1) , 5 (NP_938194.1) , 8 (NP_938198.1) , 9 (NP_938192.1) , 10 (NP_938200.1) and isoform 15 (NP_938407.1).
Immunogen Sequence: AEEISKREDASGQLS
Post Translational Modifications In response to raising of intracellular calcium, the T-type channels are activated by CaM-kinase II.
Function Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the 'low-voltage activated (LVA)' group and are strongly blocked by mibefradil. A particularity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.
Protein Name Voltage-Dependent T-Type Calcium Channel Subunit Alpha-1g
Cav3.1c
Nbr13
Voltage-Gated Calcium Channel Subunit Alpha Cav3.1
Database Links Reactome: R-HSA-419037
Reactome: R-HSA-445355
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Cytoplasm
Alternative Antibody Names Anti-Voltage-Dependent T-Type Calcium Channel Subunit Alpha-1g antibody
Anti-Cav3.1c antibody
Anti-Nbr13 antibody
Anti-Voltage-Gated Calcium Channel Subunit Alpha Cav3.1 antibody
Anti-CACNA1G antibody
Anti-KIAA1123 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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