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  • 产品名称：Anti-CACNA2D1 antibody (550-800) (STJ117455)

  • 产品型号：STJ117455
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CACNA2D1 antibody (550-800) (STJ117455)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CACNA2D1 (550-800) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:200-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CACNA2D1
Gene ID: 781
Uniprot ID: CA2D1_HUMAN
Immunogen Region: 550-800
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 550-800 of human CACNA2D1 (NP_000713.2).
Immunogen Sequence: DIKVEIRNKMIDGESGEKTF RTLVKSQDERYIDKGNRTYT WTPVNGTDYSLALVLPTYSF YYIKAKLEETITQARSKKGK MKDSETLKPDNFEESGYTFI APRDYCNDLKISDNNTEFLL NFNEFIDRKTPNNPSCNADL INRVLLDAGFTNELVQNYWS KQKNIKGVKARFVVTDGGIT RVYPKEAGENWQENPETYED SFYKRSLDNDNYVFTAPYFN KSGPGAYESGIMVSKAVEI
Tissue Specificity Isoform 1 is expressed in skeletal muscle. Isoform 2 is expressed in the central nervous system. Isoform 2, isoform 4 and isoform 5 are expressed in neuroblastoma cells. Isoform 3, isoform 4 and isoform 5 are expressed in the aorta.
Post Translational Modifications Proteolytically processed into subunits alpha-2-1 and delta-1 that are disulfide-linked.
Function The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling.
Protein Name Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-1
Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-1 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-1 - Voltage-Dependent Calcium Channel Subunit Delta-1
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Cell Membrane
Alternative Antibody Names Anti-Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-1 antibody
Anti-Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-1 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-1 - Voltage-Dependent Calcium Channel Subunit Delta-1 antibody
Anti-CACNA2D1 antibody
Anti-CACNL2A antibody
Anti-CCHL2A antibody
Anti-MHS3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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