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  • 产品名称：Anti-CACNA2D4 antibody (992-1115) (STJ114098)

  • 产品型号：STJ114098
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CACNA2D4 antibody (992-1115) (STJ114098)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CACNA2D4 (992-1115) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CACNA2D4
Gene ID: 93589
Uniprot ID: CA2D4_HUMAN
Immunogen Region: 992-1115
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 992-1115 of human CACNA2D4 (NP_758952.4).
Immunogen Sequence: AKSVFHHSHKHKKQDPLQPC DTEYPVFVYQPAIREANGIV ECGPCQKVFVVQQIPNSNLL LLVTDPTCDCSIFPPVLQEA TEVKYNASVKCDRMRSQKLR RRPDSCHAFHPEENAQDCGG ASDT
Tissue Specificity Predominantly expressed in certain types of endocrine cells. Present in the Paneth cells of the small intestine. Also present in the erythroblasts in the fetal liver, in the cells of the zona reticularis of the adrenal gland and in the basophils of the pituitary. Present at low level in some brain regions such as the cerebellum (at protein level).
Post Translational Modifications May be proteolytically processed into subunits alpha-2-4 and delta-4 that are disulfide-linked. It is however unclear whether such cleavage really takes place in vivo and has a functional role.
Function The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel.
Protein Name Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-4
Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-4 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-4 - Voltage-Dependent Calcium Channel Subunit Delta-4
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-4 antibody
Anti-Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-4 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-4 - Voltage-Dependent Calcium Channel Subunit Delta-4 antibody
Anti-CACNA2D4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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