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  • 产品名称：Anti-CDK11B antibody (1-130) (STJ114696)

  • 产品型号：STJ114696
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CDK11B antibody (1-130) (STJ114696)
详情介绍：
Host: Rabbit
Applications: WB/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CDK11B (1-130) is suitable for use in Western Blot and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
IF/ICC 1:50-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDK11B
Gene ID: 984
Uniprot ID: CD11B_HUMAN
Immunogen Region: 1-130
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human CDK11B (NP_277021.2).
Immunogen Sequence: MGDEKDSWKVKTLDEILQEK KRRKEQEEKAEIKRLKNSDD RDSKRDSLEEGELRDHRMEI TIRNSPYRREDSMEDRGEED DSLAIKPPQQMSRKEKAHHR KDEKRKEKRRHRSHSAEGGK HARVKEKERE
Tissue Specificity Expressed ubiquitously. Some evidence of isoform-specific tissue distribution.
Post Translational Modifications During FAS- or TNF-induced apoptosis, isoform SV9 is cleaved by caspases to produce p110C, a fragment that contains the C-terminal kinase domain. Phosphorylation at Ser-115 creates a binding site for 14-3-3 proteins. p110C can be autophosphorylated.
Function Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression.
Protein Name Cyclin-Dependent Kinase 11b
Cell Division Cycle 2-Like Protein Kinase 1
Clk-1
Cell Division Protein Kinase 11b
Galactosyltransferase-Associated Protein Kinase P58/Gta
Pitslre Serine/Threonine-Protein Kinase Cdc2l1
P58 Clk-1
Database Links Reactome: R-HSA-380270
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Cyclin-Dependent Kinase 11b antibody
Anti-Cell Division Cycle 2-Like Protein Kinase 1 antibody
Anti-Clk-1 antibody
Anti-Cell Division Protein Kinase 11b antibody
Anti-Galactosyltransferase-Associated Protein Kinase P58/Gta antibody
Anti-Pitslre Serine/Threonine-Protein Kinase Cdc2l1 antibody
Anti-P58 Clk-1 antibody
Anti-CDK11B antibody
Anti-CDC2L1 antibody
Anti-CDK11 antibody
Anti-PITSLREA antibody
Anti-PK58 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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