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  • 产品名称：Anti-CDKN2B antibody (1-138) (STJ27652)

  • 产品型号：STJ27652
  • 产品厂商：ST john's laboratory
  • 产品文档：
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简单介绍：
Anti-CDKN2B antibody (1-138) (STJ27652)
详情介绍：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CDKN2B (1-138) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CDKN2B
Gene ID: 1030
Uniprot ID: CDN2B_HUMAN
Immunogen Region: 1-138
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-138 of human CDKN2B (NP_004927.2).
Immunogen Sequence: MREENKGMPSGGGSDEGLAS AAARGLVEKVRQLLEAGADP NGVNRFGRRAIQVMMMGSAR VAELLLLHGAEPNCADPATL TRPVHDAAREGFLDTLVVLH RAGARLDVRDAWGRLPVDLA EERGHRDVAGYLRTATGD
Tissue Specificity Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines.
Function Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.
Protein Name Cyclin-Dependent Kinase 4 Inhibitor B
Multiple Tumor Suppressor 2
Mts-2
P14-Ink4b
P15-Ink4b
P15ink4b
Database Links Reactome: R-HSA-2173796
Reactome: R-HSA-2559580
Reactome: R-HSA-2559582
Reactome: R-HSA-2559585
Reactome: R-HSA-69231
Cellular Localisation Cytoplasm
Also Found In The Nucleus
Alternative Antibody Names Anti-Cyclin-Dependent Kinase 4 Inhibitor B antibody
Anti-Multiple Tumor Suppressor 2 antibody
Anti-Mts-2 antibody
Anti-P14-Ink4b antibody
Anti-P15-Ink4b antibody
Anti-P15ink4b antibody
Anti-CDKN2B antibody
Anti-MTS2 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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