产品详情
简单介绍:
Human RNASE7 (Ribonuclease A7) Sandwich ELISA Kit (STJE0011914)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.61ng/mL |
Detection Limit: | 1.56-100ng/mL |
Short Description: | This RNASE7 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Gene Symbol: | RNASE7 |
Gene ID: | 84659 |
Uniprot ID: | RNAS7_HUMAN |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | Expressed in collecting ducts in kidney, and in apical uroepithelium in bladder (at protein level). Expressed in various epithelial tissues including skin, respiratory tract, genito-urinary tract and, at a low level, in the gut. Expressed in liver, kidney, skeletal muscle and heart. |
Post Translational Modifications | |
Function | Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. |
Protein Name | Ribonuclease 7 Rnase 7 Skin-Derived Antimicrobial Protein 2 Sap-2 |
Database Links | Reactome: R-HSA-6803157 |
Cellular Localisation | Secreted Detected In Urine |
Alternative ELISA Names | Ribonuclease 7 ELISA kit Rnase 7 ELISA kit Skin-Derived Antimicrobial Protein 2 ELISA kit Sap-2 ELISA kit RNASE7 ELISA kit UNQ2516 ELISA kit PRO6006 ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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