产品详情
简单介绍:
Human MGMT (O-6-Methylguanine DNA Methyltransferase) Sandwich ELISA Kit Ready-To-Use (STJE0016961)
详情介绍:
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.051ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This MGMT Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 3 hrs |
Gene Symbol: | MGMT |
Gene ID: | 4255 |
Uniprot ID: | MGMT_HUMAN |
Immunogen Region: | Ready-To-Use |
Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Tissue Specificity | |
Post Translational Modifications | |
Function | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. |
Protein Name | Methylated-Dna--Protein-Cysteine Methyltransferase 6-O-Methylguanine-Dna Methyltransferase Mgmt O-6-Methylguanine-Dna-Alkyltransferase |
Database Links | Reactome: R-HSA-5657655 |
Cellular Localisation | Nucleus |
Alternative ELISA Names | Methylated-Dna--Protein-Cysteine Methyltransferase ELISA kit 6-O-Methylguanine-Dna Methyltransferase ELISA kit Mgmt ELISA kit O-6-Methylguanine-Dna-Alkyltransferase ELISA kit MGMT ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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